Across TCGA patient cohorts, ADARB1 mutation is significantly associated with the RNA expression of many other genes, with 7,111 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADARB1-associated genes across cancer lineages are MIR7843, CDCA2, and RPS27L. Each is linked with ADARB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADARB1-to-partner and partner-to-ADARB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADARB1→partner) and Y-score (partner→ADARB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR7843 →	+0.459	+5.418	<.001	.005	3	3
UCEC	CDCA2 →	+0.975	+2.807	<.001	<.001	2	4
UCEC	RPS27L →	+0.707	+2.523	<.001	<.001	3	3
UCEC	SVIP →	+0.545	+1.805	<.001	<.001	3	3
UCEC	C1orf174 →	+0.426	+3.435	<.001	<.001	3	3
COAD	PTMAP4 →	+1.610	+3.341	<.001	.005	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,111 associations by consensus.

Exploration

ADARB1 survival (RNA) · tumor vs normal (RNA) · all ADARB1 data types