ADAP1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,851 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAP1-associated genes across cancer lineages are PRDM8, PSTPIP1, and PRKCB. Each is linked with ADAP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAP1-to-partner and partner-to-ADAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAP1 versus PRDM8 in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAP1→partner) and Y-score (partner→ADAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPRDM8 →+0.983+0.746<.001<.00136
LSCCPSTPIP1 →+0.729+0.423<.001<.00135
GBMPRKCB →+1.096+0.860<.001<.00135
UCECPTAFR →+0.770+0.456<.001<.00135
UCECLPAR5 →+0.720+0.430<.001.00135
CCRCCCD84 →+0.822+0.410<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,851 associations by consensus.

ADAP1 vs PRDM8 — GBM

Per-sample scatter of ADAP1 vs PRDM8 in GBM (Pearson r = 0.53).

Explore this scatter interactively →

Exploration