ADAP1

Across TCGA cell cohorts, ADAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,923 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAP1-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Maintenance of unfolded protein, and Lipid translocation. Each is linked with ADAP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADAP1-to-partner and partner-to-ADAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by ADAP1-low versus ADAP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAP1→partner) and Y-score (partner→ADAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	-0.240	-2.674	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Maintenance of unfolded protein →	+0.138	+1.325	.001	.002	3	11
LARGE_INTESTINE	Lipid translocation →	+0.104	+2.382	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of membrane lipid distribution →	+0.094	+2.288	<.001	<.001	3	10
URINARY_TRACT	Chromosome attachment to the nuclear envelope →	+0.125	+2.024	<.001	<.001	3	10
STOMACH	NMDA selective glutamate receptor signaling pathway →	+0.284	+2.895	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,923 associations by consensus.

Establishment of epithelial cell apical/basal polarity by ADAP1 expression — URINARY_TRACT

Explore this box plot interactively →