ADAP1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ADAP1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ADAP1-associated genes across cancer lineages are OR56B1, OR9A4, and ASB17. Each is linked with ADAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAP1-to-partner and partner-to-ADAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56B1 grouped by ADAP1-low versus ADAP1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAP1→partner) and Y-score (partner→ADAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEOR56B1 →+0.012+4.977<.001.00231
SOFT_TISSUEOR9A4 →+0.017+4.369<.001.00831
OVARYASB17 →+0.023+5.807<.001.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR56B1 by ADAP1 expression — SOFT_TISSUE

Box plot of OR56B1 in ADAP1-low vs ADAP1-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration