Across TCGA cell cohorts, ADAMTSL2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ADAMTSL2-associated genes across cancer lineages are TEX47, TBC1D3H, and TXNDC8. Each is linked with ADAMTSL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTSL2-to-partner and partner-to-ADAMTSL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL2→partner) and Y-score (partner→ADAMTSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TEX47 →	+0.032	+5.415	<.001	.004	3	1
SKIN	TBC1D3H →	+0.677	+4.095	<.001	.009	3	1
LUNG_NSCLC_LUAD	TXNDC8 →	+0.006	+5.228	<.001	.005	3	1
OVARY	ARGFX →	+0.031	+5.196	<.001	.005	3	1
OVARY	SLC13A1 →	+0.006	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ADAMTSL2 survival (RNA) · tumor vs normal (RNA) · all ADAMTSL2 data types