ADAMTS8

Across TCGA patient cohorts, ADAMTS8 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,310 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADAMTS8-associated proteins across cancer lineages are PURA, CAP2, and DTNA. Each is linked with ADAMTS8 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADAMTS8-to-partner and partner-to-ADAMTS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS8 versus PURA in BRCA, with a Pearson correlation of 0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS8→partner) and Y-score (partner→ADAMTS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PURA →	+0.325	+0.377	.008	.005	2	7
HNSC	CAP2 →	+0.727	+0.472	<.001	.002	3	6
HNSC	DTNA →	+0.772	+0.383	<.001	.003	3	6
LUAD	NRDC →	-0.331	-1.116	<.001	<.001	3	6
PDAC	PEBP1 →	+0.398	+0.704	<.001	<.001	3	6
PDAC	SHANK3_S1503 →	+0.682	+0.565	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,310 associations by consensus.

ADAMTS8 vs PURA — BRCA

Explore this scatter interactively →