ADAMTS4

Across TCGA patient cohorts, ADAMTS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,999 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADAMTS4-associated proteins across cancer lineages are PPP1R18_S224, PPP1R18_S368, and PPP1R12A_S995. Each is linked with ADAMTS4 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADAMTS4-to-partner and partner-to-ADAMTS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS4 versus PPP1R18_S224 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS4→partner) and Y-score (partner→ADAMTS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R18_S224 →	+0.531	+0.747	<.001	<.001	3	9
OV	PPP1R18_S368 →	+0.976	+0.851	<.001	<.001	3	9
LSCC	PPP1R12A_S995 →	+0.542	+0.663	<.001	<.001	3	8
COAD	C6 →	+0.958	+0.996	<.001	<.001	3	8
COAD	C8A →	+0.781	+0.986	<.001	<.001	3	8
LSCC	CFH →	+0.495	+0.754	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,999 associations by consensus.

ADAMTS4 vs PPP1R18_S224 — BRCA

Explore this scatter interactively →