ADAMTS4

Across TCGA patient cohorts, ADAMTS4 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,203 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAMTS4-associated proteins across cancer lineages are TIMP3, C1QB, and F11. Each is linked with ADAMTS4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADAMTS4-to-partner and partner-to-ADAMTS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS4 versus TIMP3 in COAD, with a Pearson correlation of 0.58.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS4→partner) and Y-score (partner→ADAMTS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TIMP3 →	+1.121	+1.005	<.001	<.001	3	7
COAD	C1QB →	+0.696	+0.821	<.001	<.001	2	8
COAD	F11 →	+0.855	+1.076	<.001	<.001	3	7
BRCA	FSTL1 →	+0.575	+0.402	<.001	<.001	3	7
BRCA	HTRA1 →	+0.912	+0.390	<.001	<.001	3	7
OV	IKBIP →	+0.606	+0.903	.002	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,203 associations by consensus.

ADAMTS4 vs TIMP3 — COAD

Explore this scatter interactively →