ADAMTS4

Across TCGA cell cohorts, ADAMTS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,751 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAMTS4-associated GO terms across cancer lineages are Internal peptidyl-lysine acetylation, Positive regulation of monoatomic ion transport, and DNA topological change. Each is linked with ADAMTS4 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADAMTS4-to-partner and partner-to-ADAMTS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Internal peptidyl-lysine acetylation grouped by ADAMTS4-low versus ADAMTS4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS4→partner) and Y-score (partner→ADAMTS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Internal peptidyl-lysine acetylation →	+0.167	+1.908	<.001	<.001	3	7
BONE	Positive regulation of monoatomic ion transport →	-0.123	-1.997	<.001	.001	3	6
SOFT_TISSUE	DNA topological change →	+0.070	+0.868	.004	<.001	3	6
SOFT_TISSUE	Transcription initiation at RNA polymerase II promoter →	+0.053	+1.202	<.001	<.001	3	6
SKIN	Negative regulation of myoblast fusion →	+0.057	+1.049	<.001	.002	3	6
CNS	RISC complex assembly →	+0.048	+0.781	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,751 associations by consensus.

Internal peptidyl-lysine acetylation by ADAMTS4 expression — BONE

Explore this box plot interactively →