ADAMTS20

Across TCGA cell cohorts, ADAMTS20 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,119 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible ADAMTS20-associated GO terms across cancer lineages are Nuclear transport, Translational initiation, and mRNA 3'-end processing. Each is linked with ADAMTS20 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADAMTS20-to-partner and partner-to-ADAMTS20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by ADAMTS20-low versus ADAMTS20-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS20→partner) and Y-score (partner→ADAMTS20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear transport →	+0.066	+0.169	.004	.009	3	8
OESOPHAGUS	Translational initiation →	+0.094	+0.850	.002	.009	2	9
LUNG_SCLC	mRNA 3'-end processing →	+0.071	+0.973	<.001	.001	3	7
BONE	Establishment of RNA localization →	+0.106	+0.179	<.001	.002	3	7
LUNG_NSCLC_LUSC	Heart trabecula formation →	-0.333	-1.521	<.001	.004	3	7
BONE	RNA localization →	+0.111	+0.210	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,119 associations by consensus.

Nuclear transport by ADAMTS20 expression — BONE

Explore this box plot interactively →