ADAMTS20

Across TCGA cell cohorts, ADAMTS20 mutation is significantly associated with the RNA expression of many other genes, with 487 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADAMTS20-associated genes across cancer lineages are ZNF155, DIRC1, and NEUROD4. Each is linked with ADAMTS20 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAMTS20-to-partner and partner-to-ADAMTS20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF155 grouped by ADAMTS20-low versus ADAMTS20-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS20→partner) and Y-score (partner→ADAMTS20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ZNF155 →	-0.517	-2.459	<.001	.006	3	3
KIDNEY	DIRC1 →	+0.032	+4.954	<.001	<.001	3	2
BLOOD_Myeloma	NEUROD4 →	+0.006	+4.807	<.001	.006	3	2
LARGE_INTESTINE	CENPM →	+0.669	+2.584	.001	.002	3	2
LARGE_INTESTINE	TRMU →	+0.560	+1.949	<.001	.002	3	2
LARGE_INTESTINE	SRRM1 →	+0.559	+3.082	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 487 associations by consensus.

ZNF155 by ADAMTS20 expression — SKIN

Explore this box plot interactively →