ADAMTS2

Across TCGA cell cohorts, ADAMTS2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,049 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ADAMTS2-associated genes across cancer lineages are CERCAM, FRY, and CRYL1. Each is linked with ADAMTS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAMTS2-to-partner and partner-to-ADAMTS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS2 versus CERCAM in BLOOD_Myeloma, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS2→partner) and Y-score (partner→ADAMTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CERCAM →	+2.806	+0.883	<.001	.006	3	4
CNS	FRY →	-1.752	-0.436	.005	.007	3	4
STOMACH	CRYL1 →	-2.132	-0.565	.003	.003	2	5
LUNG_NSCLC_LUAD	CD63 →	-0.603	-0.440	<.001	<.001	3	4
LUNG_NSCLC_LUAD	LMBRD1 →	-0.666	-0.523	.004	.001	2	5
LUNG_NSCLC_LUAD	COLCA2 →	-1.073	-0.510	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,049 associations by consensus.

ADAMTS2 vs CERCAM — BLOOD_Myeloma

Explore this scatter interactively →