ADAMTS19

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADAMTS19 protein abundance is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAMTS19-associated genes across cancer lineages are GALNT16, TRDMT1, and PCDHB8. Each is linked with ADAMTS19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTS19-to-partner and partner-to-ADAMTS19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS19 versus GALNT16 in UCEC, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS19→partner) and Y-score (partner→ADAMTS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGALNT16 →+1.614+1.741<.001.00431
UCECTRDMT1 →+1.103+1.698.006.00631
UCECPCDHB8 →-1.396-2.599.002.00931
UCECSLC25A35 →+2.436+1.728.008.00531
UCECL3HYPDH →+0.618+1.701.006.00631
UCECTPGS2 →+0.560+1.701.002.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

ADAMTS19 vs GALNT16 — UCEC

Per-sample scatter of ADAMTS19 vs GALNT16 in UCEC (Pearson r = 0.82).

Explore this scatter interactively →

Exploration