ADAMTS19

Across TCGA patient cohorts, ADAMTS19 mutation is significantly associated with the RNA expression of many other genes, with 2,729 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAMTS19-associated genes across cancer lineages are HABP2, CDC25A, and LINC00987. Each is linked with ADAMTS19 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAMTS19-to-partner and partner-to-ADAMTS19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HABP2 grouped by ADAMTS19-low versus ADAMTS19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS19→partner) and Y-score (partner→ADAMTS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HABP2 →	-1.065	-1.563	.001	<.001	3	5
UCEC	CDC25A →	+0.470	+1.584	.001	<.001	3	4
UCEC	LINC00987 →	-0.324	-1.730	.001	.001	3	4
COAD	MED28P4 →	+0.164	+3.867	<.001	.001	3	3
COAD	SIGLEC27P →	+0.046	+4.070	.007	.009	3	3
LIHC	C1QBP →	+0.677	+3.216	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,729 associations by consensus.

HABP2 by ADAMTS19 expression — UCEC

Explore this box plot interactively →