ADAMTS19

Across TCGA cell cohorts, ADAMTS19 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,131 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAMTS19-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Chloride transmembrane transport, and Purine-containing compound biosynthetic process. Each is linked with ADAMTS19 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAMTS19-to-partner and partner-to-ADAMTS19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by ADAMTS19-low versus ADAMTS19-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS19→partner) and Y-score (partner→ADAMTS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Transcription initiation at RNA polymerase II promoter →	+0.035	+0.035	.001	.009	3	5
SKIN	Chloride transmembrane transport →	-0.055	-0.033	<.001	.003	3	4
BLOOD_Leukemia	Purine-containing compound biosynthetic process →	+0.044	+0.345	<.001	.003	3	4
BREAST	T-tubule organization →	-0.805	-0.734	<.001	.005	3	4
BLOOD_Leukemia	Protein insertion into membrane →	+0.052	+0.312	<.001	<.001	3	4
BLOOD_Leukemia	Purine nucleotide biosynthetic process →	+0.043	+0.349	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,131 associations by consensus.

Transcription initiation at RNA polymerase II promoter by ADAMTS19 expression — SKIN

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