ADAMTS19-AS1

Across TCGA pan-cancer cohorts, ADAMTS19-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ADAMTS19-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ADAMTS19-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADAMTS19-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and MESO show a favorable association.

THCA, UCEC, and MESO are the cancer types where ADAMTS19-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	III,IV	0.409	0.724	<.001	132	view →
UCEC	DFS	Quartile	II,III,IV	0.896	0.697	<.001	106	view →
MESO	OS	Median	All	0.667	0.422	<.001	105	view →
COAD	OS	Median	All	0.490	0.721	<.001	96	view →
KIRC	OS	Tertile	II,III,IV	0.599	0.804	<.001	72	view →
UVM	DFS	Quartile	II,III,IV	0.376	0.763	.001	70	view →
LGG	DFS	Median	All	0.810	0.659	<.001	42	view →
PAAD	OS	Quartile	All	0.719	0.362	.003	41	view →
HNSC	OS	Tertile	III,IV	0.462	0.707	.014	27	view →
STAD	DFS	Median	III,IV	0.372	0.558	.008	24	view →
BRCA	OS	Quartile	III,IV	0.960	0.810	.004	22	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ADAMTS19-AS1–THCA (DFS)

Open the THCA breakdown →