ADAMTS19-AS1

Across TCGA pan-cancer cohorts, ADAMTS19-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ADAMTS19-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ADAMTS19-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ADAMTS19-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and HNSC are the cancer types where ADAMTS19-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADAMTS19-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.365	<.001	11	view →
KIRP	Male	All	−0.425	<.001	9	view →
HNSC	All	III,IV	−0.147	.003	7	view →
BRCA	All	III,IV	+0.623	<.001	6	view →
KICH	Female	All	−0.510	<.001	5	view →
LUAD	All	III,IV	−0.118	.008	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

ADAMTS19-AS1–KIRC

Open the KIRC breakdown →