ADAMTS15

Across TCGA cell cohorts, ADAMTS15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,257 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADAMTS15-associated GO terms across cancer lineages are Renal filtration, Integrin-mediated signaling pathway, and Protein targeting to vacuole involved in autophagy. Each is linked with ADAMTS15 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADAMTS15-to-partner and partner-to-ADAMTS15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal filtration grouped by ADAMTS15-low versus ADAMTS15-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS15→partner) and Y-score (partner→ADAMTS15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Renal filtration →	+0.271	+3.457	.001	<.001	3	11
BONE	Integrin-mediated signaling pathway →	+0.234	+1.103	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Protein targeting to vacuole involved in autophagy →	+0.199	+2.475	.003	<.001	3	10
BONE	Epiboly involved in wound healing →	+0.178	+1.367	<.001	<.001	2	10
BONE	Angiogenesis →	+0.096	+1.055	<.001	<.001	3	9
BONE	Regulation of transforming growth factor beta receptor signaling pathway →	+0.073	+1.279	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,257 associations by consensus.

Renal filtration by ADAMTS15 expression — LIVER

Explore this box plot interactively →