ADAMTS10

Across TCGA cell cohorts, ADAMTS10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,462 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAMTS10-associated GO terms across cancer lineages are Protein localization to nucleus, mRNA export from nucleus, and Negative regulation of interferon-alpha production. Each is linked with ADAMTS10 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADAMTS10-to-partner and partner-to-ADAMTS10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nucleus grouped by ADAMTS10-low versus ADAMTS10-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS10→partner) and Y-score (partner→ADAMTS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein localization to nucleus →	+0.060	+1.403	.001	.004	3	11
BONE	mRNA export from nucleus →	+0.114	+1.956	.001	.004	3	10
STOMACH	Negative regulation of interferon-alpha production →	+1.274	+1.150	<.001	.003	3	10
SOFT_TISSUE	Negative regulation of calcium ion export across plasma membrane →	+0.061	+1.804	.006	.008	3	10
OVARY	IMP salvage →	+0.172	+1.209	<.001	.005	3	10
BREAST	Cell division →	+0.088	+1.654	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,462 associations by consensus.

Protein localization to nucleus by ADAMTS10 expression — STOMACH

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