ADAMTS1

Across TCGA patient cohorts, ADAMTS1 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,555 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAMTS1-associated proteins across cancer lineages are SERPING1, SHBG, and C6. Each is linked with ADAMTS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAMTS1-to-partner and partner-to-ADAMTS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS1 versus SERPING1 in LSCC, with a Pearson correlation of 0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS1→partner) and Y-score (partner→ADAMTS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SERPING1 →	+0.451	+0.485	<.001	<.001	3	4
UCEC	SHBG →	+0.626	+1.076	<.001	<.001	3	4
UCEC	C6 →	+0.534	+0.803	<.001	.002	3	4
UCEC	CP →	+0.709	+0.942	<.001	.001	3	4
CCRCC	F11 →	+0.609	+0.589	.003	<.001	2	5
CCRCC	F13B →	+0.558	+0.553	.005	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,555 associations by consensus.

ADAMTS1 vs SERPING1 — LSCC

Explore this scatter interactively →