ADAMTS1

Across TCGA cell cohorts, ADAMTS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,013 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAMTS1-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Positive regulation of vascular associated smooth muscle cell migration, and Positive regulation of cell-substrate junction organization. Each is linked with ADAMTS1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADAMTS1-to-partner and partner-to-ADAMTS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by ADAMTS1-low versus ADAMTS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS1→partner) and Y-score (partner→ADAMTS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peptidyl-lysine oxidation →	+1.326	+3.271	<.001	<.001	3	11
CNS	Positive regulation of vascular associated smooth muscle cell migration →	+0.144	+1.625	<.001	<.001	3	11
BONE	Positive regulation of cell-substrate junction organization →	+0.187	+2.595	<.001	<.001	3	10
LUNG_SCLC	Establishment of apical/basal cell polarity →	+0.142	+1.558	<.001	<.001	3	10
KIDNEY	Regulation of fibroblast proliferation →	+0.070	+1.896	<.001	.008	3	10
BONE	Viral process →	+0.106	+3.293	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,013 associations by consensus.

Peptidyl-lysine oxidation by ADAMTS1 expression — BONE

Explore this box plot interactively →