ADAMDEC1

Across TCGA cell cohorts, ADAMDEC1 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAMDEC1-associated genes across cancer lineages are OR2V2, UTF1, and OR8A1. Each is linked with ADAMDEC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMDEC1-to-partner and partner-to-ADAMDEC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2V2 grouped by ADAMDEC1-low versus ADAMDEC1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMDEC1→partner) and Y-score (partner→ADAMDEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR2V2 →	+0.053	+4.091	<.001	.002	3	2
LARGE_INTESTINE	UTF1 →	+0.015	+3.632	<.001	.003	3	1
LUNG_SCLC	OR8A1 →	+0.396	+4.044	<.001	.009	3	1
LUNG_SCLC	CXorf51A →	+0.104	+4.523	<.001	.003	3	1
BLOOD_Leukemia	IFNG →	+0.165	+3.567	<.001	.003	3	1
BLOOD_Leukemia	IL4 →	+2.124	+4.007	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OR2V2 by ADAMDEC1 expression — BLOOD_Leukemia

Explore this box plot interactively →