ADAMDEC1

Across TCGA pan-cancer cohorts, ADAMDEC1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ADAMDEC1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ADAMDEC1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ADAMDEC1 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

KIRC, HNSC, and COAD are the cancer types where ADAMDEC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADAMDEC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+2.367	<.001	12	view →
HNSC	Female	II,III,IV	+1.663	<.001	12	view →
COAD	Female	III,IV	−4.834	<.001	11	view →
LUAD	Female	All	+1.808	<.001	8	view →
STAD	Female	All	+3.178	<.001	7	view →
LUSC	Male	All	+1.938	<.001	7	view →
KIRP	Male	All	+1.503	<.001	7	view →
KICH	All	All	+1.365	<.001	7	view →
BRCA	All	II,III,IV	+1.705	<.001	6	view →
UCEC	All	All	+1.013	<.001	6	view →
READ	All	All	−3.646	<.001	5	view →
ESCA	All	All	+1.597	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ADAMDEC1–KIRC

Open the KIRC breakdown →