ADAM7

Across TCGA patient cohorts, ADAM7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,436 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ADAM7-associated proteins across cancer lineages are YY1AP1_S724, RHOT1, and RPRD2. Each is linked with ADAM7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAM7-to-partner and partner-to-ADAM7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM7 versus YY1AP1_S724 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM7→partner) and Y-score (partner→ADAM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	YY1AP1_S724 →	+0.400	+0.404	<.001	<.001	3	3
LSCC	RHOT1 →	+0.226	+0.289	<.001	.007	3	3
LSCC	RPRD2 →	+0.262	+0.480	<.001	<.001	3	3
LSCC	SCML2_S590 →	+0.872	+0.295	<.001	<.001	3	3
LSCC	GTF2E2 →	+0.341	+0.391	<.001	<.001	3	3
LSCC	MED1_S1401 →	+0.399	+0.415	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,436 associations by consensus.

ADAM7 vs YY1AP1_S724 — LSCC

Explore this scatter interactively →