Across TCGA patient cohorts, ADAM3A mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAM3A-associated genes across cancer lineages are RN7SL248P, RPS29P32, and MIR6784. Each is linked with ADAM3A in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAM3A-to-partner and partner-to-ADAM3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM3A→partner) and Y-score (partner→ADAM3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.155	+4.722	<.001	<.001	3	1
UCEC	RPS29P32 →	+0.864	+3.921	<.001	<.001	3	1
UCEC	MIR6784 →	+0.913	+3.052	.007	.003	3	1
UCEC	RNVU1-28 →	+1.166	+2.635	<.001	.008	3	1
UCEC	RN7SL478P →	+0.339	+2.676	<.001	.007	3	1
UCEC	RN7SL509P →	+0.225	+3.186	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

Exploration

ADAM3A survival (RNA) · tumor vs normal (RNA) · all ADAM3A data types