ADAM30

Across TCGA patient cohorts, ADAM30 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,380 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ADAM30-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Response to starvation, and Cellular response to salt. Each is linked with ADAM30 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADAM30-to-partner and partner-to-ADAM30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by ADAM30-low versus ADAM30-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM30→partner) and Y-score (partner→ADAM30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Establishment of protein localization to membrane →	+0.057	+0.183	<.001	.001	3	11
STAD	Response to starvation →	+0.052	+0.098	<.001	<.001	3	11
STAD	Cellular response to salt →	+0.034	+0.091	<.001	<.001	3	10
STAD	Proton transmembrane transport →	+0.055	+0.106	<.001	<.001	3	10
STAD	Ribose phosphate biosynthetic process →	+0.058	+0.108	<.001	<.001	3	10
STAD	Monosaccharide metabolic process →	+0.057	+0.117	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,380 associations by consensus.

Establishment of protein localization to membrane by ADAM30 expression — ESCA

Explore this box plot interactively →