ADAM21

Across TCGA patient cohorts, ADAM21 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,973 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAM21-associated proteins across cancer lineages are SERPINF1, HTATIP2, and IRF2BPL. Each is linked with ADAM21 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADAM21-to-partner and partner-to-ADAM21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM21 versus SERPINF1 in CCRCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM21→partner) and Y-score (partner→ADAM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SERPINF1 →	+0.729	+0.513	<.001	.001	3	4
GBM	HTATIP2 →	-0.421	-0.506	<.001	<.001	3	4
GBM	IRF2BPL →	+0.253	+0.497	<.001	<.001	3	4
LSCC	RASAL3_S51 →	-0.464	-0.524	<.001	<.001	3	4
GBM	CTSS →	-0.692	-0.774	<.001	<.001	3	4
OV	EXTL2 →	+0.564	+0.654	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,973 associations by consensus.

ADAM21 vs SERPINF1 — CCRCC

Explore this scatter interactively →