ADAM20P3

Across TCGA pan-cancer cohorts, ADAM20P3 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated ADAM20P3 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ADAM20P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADAM20P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LIHC show a favorable association.

KICH, LUAD, and CESC are the cancer types where ADAM20P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUAD	DFS	Tertile	All	0.663	0.820	<.001	84	view →
CESC	DFS	Tertile	IV	0.174	0.564	.006	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
BRCA	OS	Tertile	All	0.521	0.584	.025	30	view →
GBM	DFS	Tertile	All	0.058	0.297	<.001	21	view →
READ	DFS	Tertile	IV	0.380	0.840	.002	21	view →
SKCM	OS	Tertile	II,III,IV	0.627	0.255	.017	15	view →
LIHC	DFS	Tertile	II,III,IV	0.844	0.418	.026	15	view →
BLCA	DFS	Tertile	All	0.539	0.632	.044	12	view →
KIRP	DFS	Tertile	III,IV	1.000	0.337	.026	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

ADAM20P3–KICH (DFS)

Open the KICH breakdown →