ADAM20P3

Across TCGA pan-cancer cohorts, ADAM20P3 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ADAM20P3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ADAM20P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ADAM20P3 is over-expressed in tumor.

COAD, READ, and UCEC are the cancer types where ADAM20P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADAM20P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+0.383	<.001	10	view →
READ	Female	All	+0.376	.012	2	view →
UCEC	All	All	+0.013	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ADAM20P3–COAD

Open the COAD breakdown →