ADAM20

Across TCGA patient cohorts, ADAM20 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,267 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAM20-associated proteins across cancer lineages are CDC42BPB, CAVIN3_S62, and STRN3. Each is linked with ADAM20 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAM20-to-partner and partner-to-ADAM20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM20 versus CDC42BPB in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM20→partner) and Y-score (partner→ADAM20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC42BPB →	+0.317	+0.128	<.001	<.001	3	5
PDAC	CAVIN3_S62 →	+0.959	+0.476	.001	<.001	3	4
GBM	STRN3 →	+0.226	+0.630	<.001	.001	3	4
LSCC	TMF1 →	-0.353	-0.883	<.001	<.001	3	4
GBM	TRMT5 →	+0.429	+0.768	<.001	<.001	3	4
GBM	PLCG2 →	-0.516	-0.708	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,267 associations by consensus.

ADAM20 vs CDC42BPB — BRCA

Explore this scatter interactively →