ADAM18

Across TCGA patient cohorts, ADAM18 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,421 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ADAM18-associated GO terms across cancer lineages are Nuclear membrane reassembly, Cytokinetic process, and Ribonucleoside monophosphate biosynthetic process. Each is linked with ADAM18 in more than 12 cancer types. Because this analysis shows association rather than direction, both ADAM18-to-partner and partner-to-ADAM18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear membrane reassembly grouped by ADAM18-low versus ADAM18-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM18→partner) and Y-score (partner→ADAM18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nuclear membrane reassembly →	+0.065	+0.157	<.001	.005	2	13
STAD	Cytokinetic process →	+0.058	+0.080	<.001	<.001	3	12
ESCA	Ribonucleoside monophosphate biosynthetic process →	+0.062	+0.179	<.001	.005	3	11
STAD	Regulation of mitochondrial fission →	+0.048	+0.090	<.001	<.001	3	11
ESCA	Positive regulation of mitotic cell cycle →	+0.058	+0.132	<.001	.005	1	13
ESCA	DNA replication →	+0.070	+0.132	<.001	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,421 associations by consensus.

Nuclear membrane reassembly by ADAM18 expression — ESCA

Explore this box plot interactively →