ADAL

Across TCGA cell cohorts, ADAL mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ADAL-associated genes across cancer lineages are SPATA31D4. Each is linked with ADAL in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAL-to-partner and partner-to-ADAL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31D4 grouped by ADAL-low versus ADAL-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAL→partner) and Y-score (partner→ADAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPATA31D4 →	+0.006	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SPATA31D4 by ADAL expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →