ACYP1

Across TCGA patient cohorts, ACYP1 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACYP1-associated genes across cancer lineages are IGHV3OR16-8, MIR6839, and MIR6895. Each is linked with ACYP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACYP1-to-partner and partner-to-ACYP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHV3OR16-8 grouped by ACYP1-low versus ACYP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACYP1→partner) and Y-score (partner→ACYP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHV3OR16-8 →	+0.824	+3.757	.004	.002	3	1
UCEC	MIR6839 →	+0.238	+3.077	.002	.009	3	1
UCEC	MIR6895 →	+0.783	+3.738	.004	.002	3	1
UCEC	IGHV1OR21-1 →	+0.996	+3.970	<.001	<.001	3	1
UCEC	MIR6783 →	+0.637	+2.517	.001	.008	3	1
UCEC	MIR7155 →	+0.413	+3.472	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

IGHV3OR16-8 by ACYP1 expression — UCEC

Explore this box plot interactively →