ACVR2A

Across TCGA patient cohorts, ACVR2A protein abundance is significantly associated with the RNA expression of many other genes, with 3,271 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACVR2A-associated genes across cancer lineages are RPL24P4, DARS-AS1, and PRKAR2B. Each is linked with ACVR2A in more than 1 cancer types. Because this analysis shows association rather than direction, both ACVR2A-to-partner and partner-to-ACVR2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACVR2A versus RPL24P4 in PDAC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVR2A→partner) and Y-score (partner→ACVR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RPL24P4 →	+0.522	+0.799	.006	.001	3	2
HNSC	DARS-AS1 →	+0.667	+0.802	.004	.001	3	2
HNSC	PRKAR2B →	+0.989	+0.791	.005	.007	3	2
LSCC	GALNT14 →	+1.397	+0.477	.008	<.001	3	2
LSCC	RPRM →	+1.586	+0.535	.001	.001	3	2
LSCC	CAPN14 →	+2.046	+0.468	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

ACVR2A vs RPL24P4 — PDAC

Explore this scatter interactively →