ACVR1B

Across TCGA patient cohorts, ACVR1B protein abundance is significantly associated with the RNA expression of many other genes, with 3,130 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACVR1B-associated genes across cancer lineages are SRSF9, RNF7, and KCTD1. Each is linked with ACVR1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ACVR1B-to-partner and partner-to-ACVR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACVR1B versus SRSF9 in LSCC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVR1B→partner) and Y-score (partner→ACVR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRSF9 →	+0.371	+0.299	.002	.002	3	2
LSCC	RNF7 →	+0.430	+0.340	<.001	<.001	3	2
LSCC	KCTD1 →	+0.677	+0.248	<.001	.004	3	2
LSCC	AHSG →	+0.357	+0.267	.004	.002	3	2
GBM	KIF5A →	+1.474	+0.551	<.001	.001	3	2
LSCC	PSD3 →	+0.804	+0.355	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,130 associations by consensus.

ACVR1B vs SRSF9 — LSCC

Explore this scatter interactively →