ACVR1B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ACVR1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,799 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ACVR1B-associated GO terms across cancer lineages are Peptidyl-threonine phosphorylation, Peptidyl-threonine modification, and Regulation of myoblast fusion. Each is linked with ACVR1B in more than 13 cancer types. Because this analysis shows association rather than direction, both ACVR1B-to-partner and partner-to-ACVR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-threonine phosphorylation grouped by ACVR1B-low versus ACVR1B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVR1B→partner) and Y-score (partner→ACVR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYPeptidyl-threonine phosphorylation →+0.128+1.057<.001.002314
KIDNEYPeptidyl-threonine modification →+0.128+1.057<.001.002314
STOMACHRegulation of myoblast fusion →+0.101+0.804.003.007314
STOMACHRegulation of nucleotide-excision repair →+0.134+1.000.002.005314
BLOOD_LeukemiaCopper ion export →-0.154-0.908<.001<.001314
OESOPHAGUSRegulation of syncytium formation by plasma membrane fusion →+0.129+0.956.009.007313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,799 associations by consensus.

Peptidyl-threonine phosphorylation by ACVR1B expression — KIDNEY

Box plot of Peptidyl-threonine phosphorylation in ACVR1B-low vs ACVR1B-high samples in KIDNEY.

Explore this box plot interactively →

Exploration