Across TCGA cell cohorts, ACTRT3 mutation is significantly associated with the mutation status of many other genes, with 758 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACTRT3-associated genes across cancer lineages are QARS1, NCAPG, and OR7G1. Each is linked with ACTRT3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACTRT3-to-partner and partner-to-ACTRT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT3→partner) and Y-score (partner→ACTRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	QARS1 →	+5.014	+5.584	.003	.003	1	4
BLOOD_Lymphoma	NCAPG →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	OR7G1 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Leukemia	CORIN →	+3.672	+5.083	.001	.001	1	3
BLOOD_Leukemia	RPL7 →	+6.479	+6.479	<.001	<.001	1	3
BLOOD_Leukemia	SLC26A3 →	+3.894	+5.247	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 758 associations by consensus.

Exploration

ACTRT3 survival (RNA) · tumor vs normal (RNA) · all ACTRT3 data types