ACTR5

Across TCGA patient cohorts, ACTR5 mutation is significantly associated with the RNA expression of many other genes, with 2,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTR5-associated genes across cancer lineages are BPY2DP, RNY4P27, and MIR6803. Each is linked with ACTR5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTR5-to-partner and partner-to-ACTR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPY2DP grouped by ACTR5-low versus ACTR5-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR5→partner) and Y-score (partner→ACTR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	BPY2DP →	+0.324	+3.690	<.001	.004	3	3
HNSC	RNY4P27 →	+0.256	+4.883	<.001	.004	3	3
UCEC	MIR6803 →	+0.156	+4.603	<.001	<.001	3	2
UCEC	SNX3P1Y →	+0.070	+3.954	<.001	.006	3	2
UCEC	CENPM →	+0.506	+3.000	.007	.001	3	2
UCEC	AP1B1 →	+0.541	+2.839	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,082 associations by consensus.

BPY2DP by ACTR5 expression — STAD

Explore this box plot interactively →