ACTR3C

Across TCGA patient cohorts, ACTR3C RNA expression is significantly associated with the protein abundance of many other proteins, with 10,321 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ACTR3C-associated proteins across cancer lineages are MISP3_S208, ARMC10, and SPR. Each is linked with ACTR3C in more than 4 cancer types. Because this analysis shows association rather than direction, both ACTR3C-to-partner and partner-to-ACTR3C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR3C versus MISP3_S208 in PDAC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR3C→partner) and Y-score (partner→ACTR3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MISP3_S208 →	+0.699	+0.436	.001	.005	3	5
UCEC	ARMC10 →	+0.322	+0.524	.001	.007	3	5
UCEC	SPR →	+0.364	+0.671	.006	.005	3	5
BRCA	CDK5 →	+0.399	+0.395	<.001	.001	3	4
UCEC	GCC2 →	+0.214	+0.698	<.001	<.001	3	4
UCEC	NT5C3A →	+0.488	+0.887	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,321 associations by consensus.

ACTR3C vs MISP3_S208 — PDAC

Explore this scatter interactively →