ACTL7B

Across TCGA patient cohorts, ACTL7B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,275 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ACTL7B-associated GO terms across cancer lineages are Mitochondrial gene expression, Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and tRNA metabolic process. Each is linked with ACTL7B in more than 16 cancer types. Because this analysis shows association rather than direction, both ACTL7B-to-partner and partner-to-ACTL7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by ACTL7B-low versus ACTL7B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL7B→partner) and Y-score (partner→ACTL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.051	+0.052	<.001	<.001	3	17
UVM	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.048	+0.029	<.001	<.001	3	16
STAD	tRNA metabolic process →	+0.049	+0.049	<.001	<.001	3	16
ESCA	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.061	+0.047	<.001	.004	2	16
STAD	Peptidyl-lysine modification →	+0.046	+0.054	<.001	<.001	3	15
STAD	Positive regulation of DNA-templated transcription, elongation →	+0.050	+0.046	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,275 associations by consensus.

Mitochondrial gene expression by ACTL7B expression — STAD

Explore this box plot interactively →