ACTL7B

Across TCGA cell cohorts, ACTL7B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,675 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ACTL7B-associated GO terms across cancer lineages are Pre-mRNA catabolic process, mRNA splice site recognition, and Negative regulation of protein oligomerization. Each is linked with ACTL7B in more than 6 cancer types. Because this analysis shows association rather than direction, both ACTL7B-to-partner and partner-to-ACTL7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by ACTL7B-low versus ACTL7B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL7B→partner) and Y-score (partner→ACTL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.225	+0.029	<.001	<.001	3	7
BLOOD_Lymphoma	mRNA splice site recognition →	+0.084	+0.011	.002	.007	3	7
BLOOD_Lymphoma	Negative regulation of protein oligomerization →	+0.120	+0.014	.001	.007	3	7
BLOOD_Lymphoma	mRNA cis splicing, via spliceosome →	+0.073	+0.017	<.001	<.001	3	6
BONE	Transcription pausing by RNA polymerase II →	+0.141	+0.022	<.001	<.001	3	6
BONE	Regulation of protein oligomerization →	+0.191	+0.030	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,675 associations by consensus.

Pre-mRNA catabolic process by ACTL7B expression — BONE

Explore this box plot interactively →