Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, ACTL7A mutation is significantly associated with the RNA expression of many other genes, with 2,013 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible ACTL7A-associated genes across cancer lineages are RAC3, SH3BP1, and GCAT. Each is linked with ACTL7A in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTL7A-to-partner and partner-to-ACTL7A results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (ACTL7A→partner) and Y-score (partner→ACTL7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.