ACTL10

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACTL10 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible ACTL10-associated genes across cancer lineages are CD4+ Tem. Each is linked with ACTL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTL10-to-partner and partner-to-ACTL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by ACTL10-low versus ACTL10-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL10→partner) and Y-score (partner→ACTL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCACD4+ Tem →+0.030+5.285<.001.04931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tem by ACTL10 expression — ESCA

Box plot of CD4+ Tem in ACTL10-low vs ACTL10-high samples in ESCA.

Explore this box plot interactively →

Exploration