ACSS3

Across TCGA patient cohorts, ACSS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,761 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACSS3-associated proteins across cancer lineages are HDGFL3, LRP1, and TLN2. Each is linked with ACSS3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ACSS3-to-partner and partner-to-ACSS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSS3 versus HDGFL3 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSS3→partner) and Y-score (partner→ACSS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HDGFL3 →	+0.833	+0.396	<.001	<.001	3	7
GBM	LRP1 →	+0.415	+1.151	<.001	<.001	3	7
HNSC	TLN2 →	+0.639	+0.428	<.001	.001	3	6
GBM	TRIOBP →	+0.299	+0.730	<.001	<.001	3	6
PDAC	BDH2 →	+0.603	+0.514	<.001	<.001	3	6
HNSC	DDX21_S121 →	-0.620	-0.449	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,761 associations by consensus.

ACSS3 vs HDGFL3 — COAD

Explore this scatter interactively →