ACSM3

Across TCGA patient cohorts, ACSM3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,275 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACSM3-associated genes across cancer lineages are HELLS, FMO5, and LDHD. Each is linked with ACSM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACSM3-to-partner and partner-to-ACSM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSM3 versus HELLS in LSCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM3→partner) and Y-score (partner→ACSM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HELLS →	-0.950	-0.589	<.001	<.001	3	5
LUAD	FMO5 →	+0.987	+0.619	<.001	<.001	3	5
BRCA	LDHD →	+1.894	+1.051	<.001	.002	3	5
LSCC	XXYLT1 →	-0.553	-0.483	.003	<.001	3	5
LUAD	UBE2S →	-0.804	-0.421	<.001	.001	3	4
LSCC	VEPH1 →	+1.199	+0.691	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,275 associations by consensus.

ACSM3 vs HELLS — LSCC

Explore this scatter interactively →