ACSM2B

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ACSM2B mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ACSM2B data layer compared with 19 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ACSM2B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ACSM2B expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC are the cancer types where ACSM2B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSTertileAll0.9460.735.00555view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ACSM2B–CCRCC (OS)

Kaplan–Meier survival curve for ACSM2B mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration