ACSM2B

Across TCGA patient cohorts, ACSM2B mutation is significantly associated with the RNA expression of many other genes, with 4,029 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSM2B-associated genes across cancer lineages are CCNB1, KNSTRN, and GTSE1. Each is linked with ACSM2B in more than 5 cancer types. Because this analysis shows association rather than direction, both ACSM2B-to-partner and partner-to-ACSM2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNB1 grouped by ACSM2B-low versus ACSM2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM2B→partner) and Y-score (partner→ACSM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCNB1 →	+0.550	+1.632	.001	<.001	3	6
UCEC	KNSTRN →	+0.351	+1.668	.009	.003	3	5
LUAD	GTSE1 →	+0.729	+3.602	.007	.001	3	4
LUAD	HBQ1 →	+0.679	+2.819	.002	.001	3	4
LUAD	BIRC5 →	+0.999	+3.193	.004	.009	3	4
LUAD	CKAP2L →	+0.804	+2.819	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,029 associations by consensus.

CCNB1 by ACSM2B expression — UCEC

Explore this box plot interactively →