ACSM2B

Across TCGA patient cohorts, ACSM2B mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSM2B-associated genes across cancer lineages are PCNA, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with ACSM2B in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSM2B-to-partner and partner-to-ACSM2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by ACSM2B-low versus ACSM2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM2B→partner) and Y-score (partner→ACSM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.139	+1.362	.029	.034	3	3
UCEC	Caspase-7-cleavedD198 →	+0.449	+1.460	.010	.013	3	3
UCEC	Cyclin-B1 →	+0.472	+2.087	.004	.005	3	3
LUSC	Collagen-VI →	+0.374	+3.331	.007	.005	3	2
UCEC	Ku80 →	+0.177	+1.446	.011	.003	3	2
UCEC	mTOR_pS2448 →	-0.128	-1.439	.003	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

PCNA by ACSM2B expression — UCEC

Explore this box plot interactively →