ACSM1

Across TCGA cell cohorts, ACSM1 mutation is significantly associated with the mutation status of many other genes, with 1,221 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSM1-associated genes across cancer lineages are ZNF507, ADAMTSL1, and CNTROB. Each is linked with ACSM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACSM1-to-partner and partner-to-ACSM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF507 grouped by ACSM1-low versus ACSM1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM1→partner) and Y-score (partner→ACSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF507 →	+2.652	+3.471	.004	.004	1	4
CNS	ADAMTSL1 →	+4.459	+5.277	.005	.005	1	4
OVARY	CNTROB →	+4.415	+4.977	.007	.007	1	3
OVARY	NPBWR1 →	+5.415	+5.415	.004	.004	1	3
LARGE_INTESTINE	BNC1 →	+2.080	+3.906	.003	.003	1	3
LARGE_INTESTINE	EXOSC10 →	+2.874	+3.632	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,221 associations by consensus.

ZNF507 by ACSM1 expression — LARGE_INTESTINE

Explore this box plot interactively →