ACSL1

Across TCGA patient cohorts, ACSL1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,992 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACSL1-associated genes across cancer lineages are TLR4, PLCB2, and C1orf162. Each is linked with ACSL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ACSL1-to-partner and partner-to-ACSL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSL1 versus TLR4 in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL1→partner) and Y-score (partner→ACSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLR4 →	+0.868	+0.525	<.001	<.001	3	6
GBM	PLCB2 →	+0.903	+0.547	<.001	<.001	3	6
OV	C1orf162 →	+0.800	+0.630	<.001	<.001	3	6
GBM	VSIG4 →	+1.445	+0.585	<.001	<.001	3	6
GBM	TFEC →	+0.872	+0.598	<.001	<.001	3	5
CCRCC	DPYS →	+1.150	+0.415	.009	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,992 associations by consensus.

ACSL1 vs TLR4 — GBM

Explore this scatter interactively →